AICAR 50mg

Description

CAS Number: 2627-69-2

Disclaimer:

For research use only. Not for human consumption. Intended for laboratory-based studies by qualified professionals. The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease.

Overview:
AICAR, also known as Acadesine or AICA-riboside, is a cell-permeable nucleoside analog widely used in metabolic and cellular signaling research. It has been extensively studied for its role in AMP-activated protein kinase (AMPK) pathway modulation and is commonly used in laboratory models involving energy sensing, glucose metabolism, mitochondrial activity, and exercise-mimetic signaling.

Mechanism of Action:
Once inside the cell, AICAR is phosphorylated to ZMP, an AMP analog that can influence AMPK-related signaling pathways involved in cellular energy regulation. In research settings, AICAR is used to investigate processes linked to glucose uptake, fatty acid oxidation, autophagy, and metabolic stress responses. Researchers also note that some observed effects may extend beyond AMPK alone, making AICAR a useful but nuanced tool in pathway-focused studies.

Research Highlights:

Used in metabolic research involving AMPK pathway activation and cellular energy sensing

Studied in cell and animal models examining glucose transport, lipid metabolism, and mitochondrial function

Commonly used in exercise-mimetic and endurance-related pathway research

Investigated in studies involving autophagy, inflammatory signaling, and metabolic stress adaptation

Frequently used as a reference compound in AMPK-related experimental design

Specifications:
Form: Lyophilized powder (research-grade)
Quantity: 50mg per vial
Purity: Refer to batch-specific COA
Storage: Store as directed on the product label, sealed and protected from light and moisture

FAQ

What is AICAR 50mg studied for in research models?
AICAR is commonly studied for its involvement in AMPK-related signaling, cellular energy regulation, metabolic stress responses, glucose transport, lipid metabolism, and mitochondrial research pathways.

Is this product intended for human use?
No. This product is for laboratory research use only and is not intended for human consumption.

For research use only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.