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Description

CAS Number:
1208243-50-8

Disclaimer:
For research use only. Not for human consumption. Intended for laboratory-based studies by qualified professionals. The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure, or prevent any disease.


Overview

ARA-290, also known as cibinetide, is a synthetic research peptide derived from erythropoietin-associated signaling domains. It is primarily studied for its interaction with the innate repair receptor (IRR), a pathway associated with tissue protection, inflammatory regulation, and cellular recovery mechanisms.

Unlike erythropoietin itself, ARA-290 is engineered to selectively target tissue-protective signaling pathways without stimulating erythropoiesis-related activity. Experimental models commonly investigate ARA-290 in studies involving neuroprotective signaling, inflammatory modulation, metabolic stress adaptation, and regenerative cellular pathways.


Mechanism of Action

ARA-290 is studied for its selective activation of the innate repair receptor, a heteromeric receptor complex associated with tissue recovery and anti-inflammatory signaling. Research suggests this pathway may influence cytokine regulation, cellular stress responses, and protective signaling cascades following tissue injury or metabolic stress.

Laboratory investigations frequently examine ARA-290 in relation to nerve-associated signaling, mitochondrial stress pathways, inflammatory modulation, and regeneration-associated cellular communication.


Research Highlights

  • Studied for innate repair receptor activation
  • Investigated in inflammatory signaling research
  • Explored in tissue protection and recovery pathway studies
  • Commonly researched in neuroprotective signaling models
  • Studied for cytokine modulation and cellular stress adaptation
  • Utilized in regenerative signaling pathway investigations
  • Investigated in metabolic and mitochondrial stress research

Specifications

Form: Lyophilized powder
Grade: Research Use Only
Storage: Store in a cool, dry environment away from direct light


Research Applications

ARA-290 is commonly researched in experimental models involving:

  • Tissue protection pathways
  • Neuroprotective signaling
  • Inflammatory pathway modulation
  • Cellular recovery mechanisms
  • Cytokine-associated signaling
  • Metabolic stress adaptation
  • Regenerative cellular communication

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