VIP 10mg
<h2VIP (Vasoactive Intestinal Peptide) 10mg</h2 <pVasoactive Intestinal Peptide (VIP) is a 28amino acid neuropeptide belonging to the secretin/glucagon superfamily. Supplied as a lyophilized powder in a sterile 10mg vial, verified at ≥99% purity by HPLC. VIP is among the most extensively studied neuropeptides in preclinical research, with documented roles in vasodilation, neuromodulation, immune regulation, and circadian rhythm control.</p <h3Molecular Profile</h3 <ul <li<strongSequence:</strong HisSerAspAlaValPheThrAspAsnTyrThrArgLeuArgLysGlnMetAlaValLysLysTyrLeuAsnSerIleLeuAsnNH₂</li <li<strongMolecular Formula:</strong C₁₄₇H₂₃₇N₄₃O₄₃S</li <li<strongMolecular Weight:</strong 3325.8 Da</li <li<strongCAS Number:</strong 37221797</li <li<strongReceptor targets:</strong VPAC1 (VIPR1), VPAC2 (VIPR2) — Gprotein coupled receptors</li </ul <h3Preclinical & In Vitro Data</h3 <ul <liPotent vasodilatory activity in vascular smooth muscle cell models; activates adenylyl cyclase via Gscoupled VPAC receptors</li <liImmunomodulatory effects documented in macrophage and Tcell culture models — shifts cytokine profiles toward antiinflammatory (IL10 upregulation, TNFα suppression)</li <liNeuroprotective properties studied in neuronal cell lines; shown to inhibit apoptosis via MAPK/ERK and PI3K/Akt pathways</li <liCircadian rhythm research: VIP is the primary synchronizing signal in the suprachiasmatic nucleus (SCN) in rodent models</li <liBronchodilatory effects observed in airway smooth muscle preparations</li <liStudied in models of inflammatory bowel disease, pulmonary hypertension, and autoimmune conditions</li </ul <h3Specifications</h3 <ul <liForm: Lyophilized powder</li <liAmount: 10mg per vial</li <liPurity: ≥99% (HPLCverified)</li <liStorage: 20°C (lyophilized); reconstituted solutions stable at 4°C for up to 7 days</li <liSolubility: Soluble in sterile water or PBS at ≥1mg/mL</li </ul <p<strongFor Research Use Only. Not for Human Consumption.</strong</p Purity specification: ≥99% Purity HPLC. CAS number: 475108-18-0. Category: Neuropeptides.
For research use only. Not for human consumption.